What is the Choline glycerophosphate?

Choline glycerophosphate is White waxy solid, while it's Molecular Formula is C8H20NO6P. White waxy solid L-α-Glycerophosphorylcholine has been used to rescue choline auxotrophy. It has also been used for the synthesis of glycerophospholipids.

What is the CAS number for Choline glycerophosphate?

The CAS number of Choline glycerophosphate is 28319-77-9.

What is Choline glycerophosphate (28319-77-9) used for?

Choline alfoscerate is a nootropic reportedly effective in the treatment of age-associatedmemory impairment. In man, it decreased and prevented scopolamine-inducedamnesia. In vitro studies suggest that choline alfoscerate acts indirectly on cholinergictransmission by elevating the synthesis of acetylcholine.InChI:InChI=1/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1

Quality Manufacturer Supply Factory Sells Choline glycerophosphate 28319-77-9 Customized Supply

Product Details

Quick Details

CasNo： 28319-77-9
Molecular Formula： C₈H₂₀NO₆P
Appearance： White waxy solid
Purity： 99%

Quality Manufacturer Supply Factory Sells Choline glycerophosphate 28319-77-9 Customized Supply

Molecular Formula:C8H20NO6P
Molecular Weight:257.224
Appearance/Colour:White waxy solid
Vapor Pressure:0Pa at 25℃
Melting Point:-98oC
Boiling Point:480℃[at 101 325 Pa]
Flash Point:11 °C
PSA：108.86000
LogP:-0.38240

Choline glycerophosphate(Cas 28319-77-9) Usage

Description	Choline alfoscerate is a nootropic reportedly effective in the treatment of age-associated memory impairment. In man, it decreased and prevented scopolamine-induced amnesia. In vitro studies suggest that choline alfoscerate acts indirectly on cholinergic transmission by elevating the synthesis of acetylcholine.
Chemical Properties	White waxy solid
Originator	Sandoz; Italfarmaco (Italy)
Uses	sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-Glycero-3-phosphocholine is used as an Nootropic.
Definition	ChEBI: A member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells.
Brand name	Delecit
General Description	L-α-Glycerophosphorylcholine is a phospholipid, which is a derivative of phosphatidylcholine.
Flammability and Explosibility	Notclassified
Biochem/physiol Actions	Increases inositol phosphate formation.

InChI:InChI=1/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1

28319-77-9 Relevant articles

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Baer,Kates

, p. 1394,1396 (1948)

Preparation method of glycerophosphocholine

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Paragraph 0028-0032; 0033-0037; 0038-0042; 0043-0047, (2021/09/08)

The invention discloses a preparation me...

METHOD OF PREPARING CHOLINE ALFOSCERATE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

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Paragraph 0113-0141, (2020/10/27)

The present invention relates to a metho...

Synthesis method for compound choline alfoscerate for promoting brain functions

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Paragraph 0025, (2019/11/21)

The invention discloses a synthesis meth...

Method of preparing L-alpha-glycerol phosphatidylcholine

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Paragraph 0087; 0089; 0091; 0093, (2018/06/26)

The invention provides a method of prepa...

28319-77-9 Process route

: 57090-45-6
(2R)-3-chloro-1,2-propanediol

: 107-73-3
phosphorylcholine chloride

: 28319-77-9,563-24-6
L-glycero-3-phosphorylcholine

Conditions

Conditions	Yield
phosphorylcholine chloride; With potassium hydroxide; In methanol; for 1h; (2R)-3-chloro-1,2-propanediol; In methanol; at 65 ℃; for 16h; Temperature;	99%
phosphorylcholine chloride; With potassium hydroxide; In ethanol; for 0.5h; (2R)-3-chloro-1,2-propanediol; In ethanol; at 75 - 85 ℃; for 6h;	79.6%