What is the 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole?

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole is Pale Yellow Solid, while it's Molecular Formula is C8H6F2N2OS. Pale Yellow Solid Pantoprazole EP Impurity C. Pantoprazole USP Related Compound C.

What is the CAS number for 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole?

The CAS number of 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole is 97963-62-7.

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Product Details

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CasNo： 97963-62-7
Molecular Formula： C₈H₆F₂N₂OS
Appearance： Pale Yellow Solid
Purity： 99%

Quality Manufacturer Supply Buy High Quality 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97963-62-7 with Efficient Shipping

Molecular Formula:C8H6F2N2OS
Molecular Weight:216.211
Appearance/Colour:Pale Yellow Solid
Vapor Pressure:0.000928mmHg at 25°C
Melting Point:239-243 °C(lit.)
Refractive Index:1.63
Boiling Point:303.5 °C at 760 mmHg
PKA:9.77±0.30(Predicted)
Flash Point:137.3 °C
PSA：76.71000
Density:1.52 g/cm³
LogP:2.45300

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole(Cas 97963-62-7) Usage

Chemical Properties	Pale Yellow Solid
Uses	Pantoprazole EP Impurity C. Pantoprazole USP Related Compound C.
General Description	5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole may be used in the synthesis of pantoprazole, a drug for treating gastroesophageal reflux disease and gastrointestinal disorders.

InChI:InChI=1/C8H6F2N2OS/c9-7(10)13-4-1-2-5-6(3-4)12-8(14)11-5/h1-3,7H,(H2,11,12,14)

97963-62-7 Relevant articles

Synthesis and antimicrobial evaluations of sulfur inserted fluoro-benzimidazoles

Dwivedi, Parmesh Kumar,Chaturvedi, Devdutt

, p. 1525 - 1529 (2021/07/02)

A new series of fluorinated sulfur inser...

Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies

Sana, Sravani,Reddy, Velma Ganga,Srinivasa Reddy,Tokala, Ramya,Kumar, Rahul,Bhargava, Suresh K.,Shankaraiah, Nagula

, (2021/03/15)

An approach in modern medicinal chemistr...

Preparation method of 4- polyfluoro methoxy O-phenylenediamine (by machine translation)

-

Paragraph 0015, (2020/01/03)

The method disclosed by the invention 4 ...

Triple Mode of Alkylation with Ethyl Bromodifluoroacetate: N, or O-Difluoromethylation, N-Ethylation and S-(ethoxycarbonyl)difluoromethylation

Polley, Arghya,Bairy, Gurupada,Das, Pritha,Jana, Ranjan

supporting information, p. 4161 - 4167 (2018/09/21)

In this report, we have explored a tripl...

97963-62-7 Process route

: 75-15-0,12122-00-8
carbon disulfide

: 172282-50-7
4-(difluoromethoxy)benzene-1,2-diamine

: 97963-62-7
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

Conditions

Conditions	Yield
4-(difluoromethoxy)benzene-1,2-diamine; With sodium carbonate; In water; for 0.333333h; Reflux; Green chemistry; carbon disulfide; In water; at 25 - 70 ℃; for 12h; Temperature; Reagent/catalyst; Green chemistry;	95.4%
With sodium hydroxide; In methanol; for 4h; Reflux;	94.5%
With potassium hydroxide; In ethanol;	52%
With sodium carbonate; In water; at 20 - 70 ℃; for 12h;	77 mg
In ethanol; at 60 ℃; for 5h;

: 577-71-9
3,4-dinitophenol

: 97963-62-7
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: caesium carbonate / N,N-dimethyl-formamide / 20 °C 2: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C 3: sodium carbonate / water / 12 h / 20 - 70 °C With palladium 10% on activated carbon; hydrogen; sodium carbonate; caesium carbonate; In methanol; water; N,N-dimethyl-formamide;

97963-62-7 Upstream products

75-15-0
carbon disulfide
172282-50-7
4-(difluoromethoxy)benzene-1,2-diamine
577-71-9
3,4-dinitophenol
103-90-2
4-acetaminophenol

97963-62-7 Downstream products

97964-24-4
5-Difluoromethoxy-2-(4-methoxy-3-methyl-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
102625-64-9
pantoprazole sulfide
102625-62-7
5-difluoromethoxy-2-[(4,5-dimethoxy-3-methyl-pyridin-2-yl)methylthio]-1H-benzimidazole
953787-51-4
5-(difluoromethoxy)-2-[[(3,4-dimethoxypyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzoimidazole

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97963-62-7

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Quality Manufacturer Supply Buy High Quality 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97963-62-7 with Efficient Shipping

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole(Cas 97963-62-7) Usage

97963-62-7 Relevant articles

Synthesis and antimicrobial evaluations of sulfur inserted fluoro-benzimidazoles

Dwivedi, Parmesh Kumar,Chaturvedi, Devdutt

, p. 1525 - 1529 (2021/07/02)

Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies

Sana, Sravani,Reddy, Velma Ganga,Srinivasa Reddy,Tokala, Ramya,Kumar, Rahul,Bhargava, Suresh K.,Shankaraiah, Nagula

, (2021/03/15)

Preparation method of 4- polyfluoro methoxy O-phenylenediamine (by machine translation)

-

Paragraph 0015, (2020/01/03)

Triple Mode of Alkylation with Ethyl Bromodifluoroacetate: N, or O-Difluoromethylation, N-Ethylation and S-(ethoxycarbonyl)difluoromethylation

Polley, Arghya,Bairy, Gurupada,Das, Pritha,Jana, Ranjan

supporting information, p. 4161 - 4167 (2018/09/21)

97963-62-7 Process route

97963-62-7 Upstream products

97963-62-7 Downstream products

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