Your Location：Home >Products >Fine chemicals >80841-78-7

80841-78-7

  • Product Name4-Cloromethyl-5-methyl-1,3-dioxol-2-one
  • Molecular FormulaC5H5ClO3
  • Molecular Weight148.546
  • Purity99%
  • AppearancePale yellow transparent liquid
Inquiry

Product Details

Quick Details

  • CasNo： 80841-78-7
  • Molecular Formula： C5H5ClO3
  • Appearance： Pale yellow transparent liquid
  • Purity： 99%

Trustworthy Manufacturer Supply Top Purity 99% 4-Cloromethyl-5-methyl-1,3-dioxol-2-one 80841-78-7 Customized Supply

  • Molecular Formula:C5H5ClO3
  • Molecular Weight:148.546
  • Appearance/Colour:Pale yellow transparent liquid 
  • Vapor Pressure:2.085mmHg at 25°C 
  • Refractive Index:1.481 
  • Boiling Point:163.228 °C at 760 mmHg 
  • Flash Point:66.729 °C 
  • PSA：43.35000 
  • Density:1.362 g/cm3 
  • LogP:1.28000 

4-Cloromethyl-5-methyl-1,3-dioxol-2-one(Cas 80841-78-7) Usage

Chemical Properties

4-Cloromethyl-5-methyl-1,3-dioxol-2-one is Pale Yellow Oil

Uses

4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.

InChI:InChI=1/C5H5ClO3/c1-3-4(2-6)9-5(7)8-3/h2H2,1H3

80841-78-7 Relevant articles

Preparation method of olmesartan medoxomil key intermediate

-

Paragraph 0017-0025, (2021/08/07)

The invention discloses a preparation me...

Method for catalytically synthesizing high-purity 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0027-0038, (2020/07/06)

The invention belongs to the technical f...

A 4 - chloro methyl -5 - methyl - 1, 3 - dioxo heterocyclic pentene -2 - one purification method

-

Paragraph 0023-0050, (2019/03/21)

The invention discloses a purification m...

Preparation method for 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0015-0022, (2018/04/21)

The invention specifically relates to a ...

80841-78-7 Process route

4,5-Dimethyl-1,3-dioxole-2-one
37830-90-3

4,5-Dimethyl-1,3-dioxole-2-one

4-chloromethyl-5-methyl-1,3-dioxol-2-one
80841-78-7

4-chloromethyl-5-methyl-1,3-dioxol-2-one

Conditions
Conditions Yield
With chlorine; In 1,2-dichloro-ethane; for 0.5h; Solvent; Reagent/catalyst; Reflux; Molecular sieve;
89.3%
With N-chloro-succinimide; In tetrachloromethane; for 80h; Ambient temperature; Irradiation;
9.2%
With chlorine; copper; Yield given. Multistep reaction; 1.) dichloromethane, 90 min, reflux, 2.) dichloromethane, 2 h, reflux;
 
With sulfuryl dichloride; In dichloromethane;
 
With N-chloro-succinimide; dibenzoyl peroxide; at 90 ℃; for 5.5h; Temperature; Solvent; Large scale;
326 g
With 2,2'-azobis(isobutyronitrile); trichloroisocyanuric acid; In dichloromethane; for 3h; Reagent/catalyst; Irradiation; Reflux; Large scale;
 
4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one
95579-71-8

4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one

4-chloromethyl-5-methyl-1,3-dioxol-2-one
80841-78-7

4-chloromethyl-5-methyl-1,3-dioxol-2-one

Conditions
Conditions Yield
at 75 - 80 ℃; for 4h;
87%
 
  
at 85 ℃; Temperature;
53.3 g

80841-78-7 Upstream products

  • 37830-90-3
    37830-90-3

    4,5-Dimethyl-1,3-dioxole-2-one

  • 95579-71-8
    95579-71-8

    4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one

80841-78-7 Downstream products

  • 111738-35-3
    111738-35-3

    4-(4-Fluorophenyl)thiomethyl-5-methyl-1,3-dioxol-2-one

  • 111738-30-8
    111738-30-8

    4-(4-Methoxyphenyl)thiomethyl-5-methyl-1,3-dioxol-2-one

  • 111738-22-8
    111738-22-8

    Sodium 4-((5-Methyl-2-oxo-1,3-dioxol-4-yl)methylthio)benzenesulfonate

  • 111738-26-2
    111738-26-2

    2-Chloro-5-((5-methyl-2-oxo-1,3-dioxol-4-yl)methylthio)benzoic Acid

;

Relevant Products

Contact Now

Submit

Contact us

Address:3rd Building, Hua Yi Road 76 Zhangjiang Pudong New Area Shanghai

Tel:+86-13701882790

Phone:请录入手机号

QQ:请录入QQ

Email:sales@scochem.com

Maps

Home About us Products Amino acid Contact Us

links

Copyright @2009-2024 Shanghai Scochem Technology Co., Ltd ICP NO.:Zhejiang000000