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Product Details
Description |
Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity. It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application. Bemotrizinol is commonly marketed as Tinosorb S and Escalol S. |
Uses |
Bemotrizinol is a broad-spectrum UV absorber, absorbing both UVA and UVB. Bemotrizinol is added to various sunscreens to absorb UV rays. |
Brand name |
Tinosorb S (Ciba Specialty Chemicals). |
Flammability and Explosibility |
Nonflammable |
Safety |
Because bemotrizinol is relatively new to the sunscreen market there are few reports or studies available documenting its adverse effects and long term use. Studies to date have shown it to have a good safety profile. It is not significantly absorbed into the skin and rarely causes skin irritation. Unlike some other organic sunscreen agents, in vitro studies show that bemotrizinol does not appear to have hormonal effects. Further long-term human safety studies are required. |
Regulations |
Bemotrizinol is approved for use in Europe and Australasia. It is marketed under the brand names Tinosorb S and Escalol S. It is currently awaiting FDA approval so is not available in the USA. |
InChI:InChI:1S/C38H49N3O5/c1-6-10-12-26(8-3)24-45-30-18-20-32(34(42)22-30)37-39-36(28-14-16-29(44-5)17-15-28)40-38(41-37)33-21-19-31(23-35(33)43)46-25-27(9-4)13-11-7-2/h14-23,26-27,42-43H,6-13,24-25H2,1-5H3
The invention particularly discloses a p...
The invention discloses an etherificatio...
The present invention relates to a triaz...
The present invention relates to a triaz...
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine
recorcinol
tinosorb S
4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol
Conditions | Yield |
---|---|
aluminium chloride; In sulfolane; methanol; 5,5-dimethyl-1,3-cyclohexadiene;
|
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine
3-ethylhexyloxyphenol
tinosorb S
Conditions | Yield |
---|---|
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine; 3-ethylhexyloxyphenol; With aluminum (III) chloride; In chlorobenzene; at 40 - 60 ℃;
In water; at 40 - 60 ℃;
|
91.9% |
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine
recorcinol
3-(chloromethyl)heptane
4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol
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