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96797-15-8

  • Product Name4-Iodo-1-tritylimidazole
  • Molecular FormulaC22H17 I N2
  • Molecular Weight436.295
  • Purity99%
  • Appearanceoff-white solid.
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Product Details

Quick Details

  • CasNo: 96797-15-8
  • Molecular Formula: C22H17 I N2
  • Appearance: off-white solid.
  • Purity: 99%

Factory Supply High Purity Factory Sells 4-Iodo-1-tritylimidazole 96797-15-8 Customized Supply

  • Molecular Formula:C22H17 I N2
  • Molecular Weight:436.295
  • Appearance/Colour:off-white solid. 
  • Vapor Pressure:5.3E-10mmHg at 25°C 
  • Melting Point:223ºC 
  • Boiling Point:509.7 °C at 760 mmHg 
  • PKA:3.80±0.61(Predicted) 
  • Flash Point:262 °C 
  • PSA:17.82000 
  • Density:1.4 g/cm3 
  • LogP:5.32790 

4-Iodo-1-tritylimidazole(Cas 96797-15-8) Usage

Uses

4-Iodo-1-tritylimidazole is a compound useful in organic synthesis.

Chemical Properties

White Solid

InChI:InChI=1/C22H17IN2/c23-21-16-25(17-24-21)22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-17H

96797-15-8 Relevant articles

Preparation method of (2-(1H-imidazole-4-yl)phenyl)methanol

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Paragraph 0031-0046, (2021/01/04)

The invention belongs to the technical f...

DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST

-

Paragraph 0826-0828, (2020/07/07)

The present application belongs to the f...

Design and synthesis of indoleamine 2,3-dioxygenase 1 inhibitors and evaluation of their use as anti-tumor agents

Wen, Hui,Liu, Yuke,Wang, Shufang,Wang, Ting,Zhang, Gang,Chen, Xiaoguang,Li, Yan,Cui, Huaqing,Lai, Fangfang,Sheng, Li

, (2019/06/11)

Indoleamine 2,3-dioxygenase (IDO) 1 is t...

OGA INHIBITOR COMPOUNDS

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Page/Page column 87, (2020/01/11)

The present invention relates to O-GIcNA...

96797-15-8 Process route

4-iodoimidazole
71759-89-2

4-iodoimidazole

trityl chloride
76-83-5

trityl chloride

N-trityl-4<sup>(5)</sup>-iodoimidazole
96797-15-8

N-trityl-4(5)-iodoimidazole

Conditions
Conditions Yield
With triethylamine; In N,N-dimethyl-formamide; at 20 - 25 ℃; for 22h; Solvent; Reagent/catalyst; Temperature;
97.2%
With triethylamine; In N,N-dimethyl-formamide; Ambient temperature;
95%
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
94%
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
94%
With triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 48h;
93%
With triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 48h;
93%
With triethylamine; In dichloromethane; at 25 ℃; for 17h; Cooling with ice; Inert atmosphere;
93%
With triethylamine; In dichloromethane; at 25 ℃; for 17h; Inert atmosphere;
93%
With triethylamine; In dichloromethane; at 25 ℃; for 17h; Inert atmosphere;
93%
In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;
92%
4-iodoimidazole; With triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;
trityl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
92%
In ISOPROPYLAMIDE; at 0 - 20 ℃;
90%
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 48h;
88.9%
With triethylamine; In dichloromethane; at 20 ℃; for 15h;
88%
With triethylamine; In tetrahydrofuran; at 70 ℃; for 3h; Inert atmosphere;
81%
With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
78%
With triethylamine; In N,N-dimethyl-formamide; Ambient temperature;
76%
With triethylamine; In tetrahydrofuran; at 80 ℃;
71%
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 14h;
66%
With triethylamine; In tetrahydrofuran; for 1.5h; Reflux;
64%
With triethylamine; In water; N,N-dimethyl-formamide;
59%
4-iodoimidazole; With triethylamine; In dichloromethane; at 20 ℃; for 0.0833333h;
trityl chloride; In dichloromethane; at 40 ℃; for 16h;
58%
With triethylamine; In tetrahydrofuran; at 70 ℃; for 3h;
55.57%
With triethylamine; In tetrahydrofuran;
 
 
 
With triethylamine; In dichloromethane;
 
With triethylamine; In N,N-dimethyl-formamide;
 
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
 
4-iodoimidazole
71759-89-2

4-iodoimidazole

diethyl ether
60-29-7,927820-24-4

diethyl ether

trityl chloride
76-83-5

trityl chloride

N-trityl-4<sup>(5)</sup>-iodoimidazole
96797-15-8

N-trityl-4(5)-iodoimidazole

Conditions
Conditions Yield
In N,N-dimethyl-formamide;
92%

96797-15-8 Upstream products

  • 71759-89-2
    71759-89-2

    4-iodoimidazole

  • 76-83-5
    76-83-5

    trityl chloride

  • 60-29-7
    60-29-7

    diethyl ether

96797-15-8 Downstream products

  • 135773-29-4
    135773-29-4

    5-Hydroxy-5-(1-trityl-1H-imidazol-4-yl)-pentanoic acid methyl ester

  • 151607-58-8
    151607-58-8

    1,1-Bis(methylthio)-2-fluoro-3-((1'-trityl)-4'-imidazolyl)prop-1-en-3-ol

  • 135773-27-2
    135773-27-2

    1-triphenylmethyl-4-[(1-hydroxy-1-phenyl)methyl]-1H-imidazole

  • 62256-50-2
    62256-50-2

    alpha-methyl-1-triphenylmethyl-1H-imidazole-4-methanol

;