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173772-63-9

  • Product Name2,4-DICHLORO-3-AMINOPYRIDINE
  • Molecular FormulaC5H4Cl2N2
  • Molecular Weight163.006
  • Purity99%
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  • CasNo： 173772-63-9
  • Molecular Formula： C5H4Cl2N2
  • Purity： 99%

Factory Supply High Purity 2,4-DICHLORO-3-AMINOPYRIDINE 173772-63-9 with the Best Price

  • Molecular Formula:C5H4Cl2N2
  • Molecular Weight:163.006
  • Boiling Point:264.977 °C at 760 mmHg 
  • PKA:0.72±0.10(Predicted) 
  • Flash Point:114.054 °C 
  • PSA：38.91000 
  • Density:1.498 g/cm3 
  • LogP:2.55180 

173772-63-9 Relevant articles

Heterocyclic compound as well as pharmaceutical composition, preparation method, intermediate and application thereof

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Paragraph 0933-0934; 0945-0974, (2021/06/23)

The invention discloses a heterocyclic c...

HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C

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Page/Page column 108, (2021/01/23)

Provided are heterocyclic compounds as i...

Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway

Tantry, Subramanyam J.,Shinde, Vikas,Balakrishnan, Gayathri,Markad, Shankar D.,Gupta, Amit K.,Bhat, Jyothi,Narayan, Ashwini,Raichurkar, Anandkumar,Jena, Lalit Kumar,Sharma, Sreevalli,Kumar, Naveen,Nanduri, Robert,Bharath, Sowmya,Reddy, Jitendar,Panduga, Vijender,Prabhakar,Kandaswamy, Karthikeyan,Kaur, Parvinder,Dinesh, Neela,Guptha, Supreeth,Saralaya, Ramanatha,Panda, Manoranjan,Rudrapatna, Suresh,Mallya, Meenakshi,Rubin, Harvey,Yano, Takahiro,Mdluili, Khisi,Cooper, Christopher B.,Balasubramanian,Sambandamurthy, Vasan K.,Ramachandran, Vasanthi,Shandil, Radha,Kavanagh, Stefan,Narayanan, Shridhar,Iyer, Pravin,Mukherjee, Kakoli,Hosagrahara, Vinayak P.,Solapure, Suresh,Hameed, P.Shahul,Ravishankar, Sudha

supporting information, p. 1022 - 1032 (2016/06/08)

The success of bedaquiline as an anti-tu...

INHIBITORS OF IAP

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, (2011/04/14)

The invention provides novel inhibitors ...

173772-63-9 Process route

2,4-dichloro-3-nitro-pyridine
5975-12-2

2,4-dichloro-3-nitro-pyridine

2,4-dichloropyridin-3-ylamine
173772-63-9

2,4-dichloropyridin-3-ylamine

Conditions
Conditions Yield
With hydrogenchloride; tin(ll) chloride; In diethyl ether; at 20 ℃; for 2h;
92%
With hydrogenchloride; tin(ll) chloride; In diethyl ether; at 20 ℃;
90%
2,4-dichloro-3-nitro-pyridine; With iron; acetic acid; at 40 ℃; for 2h;
With sodium hydrogencarbonate; In water;
87%
2,4-dichloro-3-nitro-pyridine; With iron; acetic acid; at 40 ℃; for 2h;
With water; sodium hydrogencarbonate; at 0 ℃;
87%
With water; iron; ammonium chloride; In ethanol; at 80 ℃; for 5h;
82.08%
With iron; acetic acid;
 
With iron; acetic acid; at 40 ℃; for 3h;
 
C<sub>19</sub>H<sub>29</sub>N<sub>7</sub>O<sub>3</sub>*C<sub>2</sub>HF<sub>3</sub>O<sub>2</sub>

C19H29N7O3*C2HF3O2

(E)-4-(dimethylamino)-2-butenoic acid hydrochloride
1130155-48-4

(E)-4-(dimethylamino)-2-butenoic acid hydrochloride

2,4-dichloropyridin-3-ylamine
173772-63-9

2,4-dichloropyridin-3-ylamine

Conditions
Conditions Yield
With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;
70 mg

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