Reputable Factory Supply High Purity 72-40-2 with Reasonable Price

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CasNo： 72-40-2
Purity： 99%

Reputable Factory Supply High Purity 72-40-2 4-Amino-5-imidazolecarboxamide hydrochloride with Reasonable Price

Molecular Formula:C4H7ClN4O
Molecular Weight:162.579
Appearance/Colour:very slightly beige fine powder
Vapor Pressure:5.33E-11mmHg at 25°C
Melting Point:250-252 °C (dec.)(lit.)
Boiling Point:522.1 °C at 760 mmHg
Flash Point:269.6 °C
PSA：97.79000
LogP:1.17430

4-Amino-5-imidazolecarboxamide hydrochloride(Cas 72-40-2) Usage

General Description

4-Amino-5-imidazolecarboxamide hydrochloride, also known as AICA ribonucleotide or ZMP, serves several key roles across various domains. Primarily recognized as an intermediate in the purine biosynthetic pathway, it has garnered interest in medicinal chemistry due to its potential therapeutic applications.

Uses

Researchers have explored its use in metabolic disorders, such as diabetes and obesity, as it activates AMP-activated protein kinase (AMPK), a cellular energy sensor that regulates glucose and lipid metabolism. Additionally, it has been investigated for its neuroprotective effects in conditions like ischemic stroke and neurodegenerative diseases. Beyond its role in medicine, AICA ribonucleotide has found utility in biochemical research as a tool for studying AMPK activation and cellular energy metabolism pathways, further underscoring its significance in both basic science and clinical investigations.

72-40-2 Relevant articles

Development of a One-Step Synthesis of 5-Amino-1 H-imidazole-4-carboxamide

Qi, Ji,Yin, Jingjun,Li, Donghong,Chen, Song,Liu, Zhenguo

, p. 591 - 596 (2021/04/05)

An innovative and efficient synthesis of...

PROCESS FOR THE PREPARATION OF TETRAZINE DERIVATIVES

-

, (2011/10/10)

The present invention provides a process...

72-40-2 Upstream products

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5-Aminoimidazole-4-carboxamide

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5-Acetamidoimidazole-4-carboxamide

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72-40-2

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Reputable Factory Supply High Purity 72-40-2 4-Amino-5-imidazolecarboxamide hydrochloride with Reasonable Price

4-Amino-5-imidazolecarboxamide hydrochloride(Cas 72-40-2) Usage

72-40-2 Relevant articles

Development of a One-Step Synthesis of 5-Amino-1 H-imidazole-4-carboxamide

Qi, Ji,Yin, Jingjun,Li, Donghong,Chen, Song,Liu, Zhenguo

, p. 591 - 596 (2021/04/05)

PROCESS FOR THE PREPARATION OF TETRAZINE DERIVATIVES

-

, (2011/10/10)

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